GRIA2 抗体 (pSer880)
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Quick Overview for GRIA2 抗体 (pSer880) (ABIN372656)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer880
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特异性
- This antibody is specific for the ~100k phosphorylated at Ser880.
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交叉反应 （详细）
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Species reactivity (expected):Chicken, Human, Mouse, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat. -
纯化方法
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser880 of rat GluR2.
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody
GRIA2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7G6 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 35-175) antibodyGRIA2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A7A3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 413-527) antibodyGRIA2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 175-430) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibodyGRIA2 适用: 大鼠 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S21-32 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Extracellular), (N-Term) antibodyGRIA2 适用: 大鼠 WB, IF, IC, LCI 宿主: 豚鼠 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Extracellular), (N-Term) antibodyKO Validated GRIA2 适用: 大鼠 WB, IHC, IP, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- Glutamate Receptor 2 / GLUR2
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背景
- The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990, Hollmann and Heinemann, 1994). The number of GluR2 subunits in the AMPA receptor complex affects the Ca2+ permeability, rectification and single-channel conductance of AMPA receptors. Ser880 has been identified as the PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1 (Matsuda et al., 1999)Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic
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基因ID
- 29627
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NCBI登录号
- NP_001077280
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UniProt
- P19491
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途径
- PI3K-Akt Signaling
抗原
-
