GRIA2 抗体 (C-Term)
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Quick Overview for GRIA2 抗体 (C-Term) (ABIN372655)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is specific for the ~100k GluR2/3 protein.
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交叉反应 (详细)
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Species reactivity (expected):Chicken, Human, Mouse and Zebrafish.
Species reactivity (tested):Rat.
Also reacts to: GLUR3 -
纯化方法
- Affinity Chromatography.
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免疫原
- Peptide corresponding to amino acid residues from the C-terminal region of rat GluR2/3.
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亚型
- IgG
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应用备注
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Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- Glutamate Receptor 2 / GLUR2
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背景
- The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003,Seidenman et al., 2003,Chung et al., 2003,Yan et al., 2002).Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic
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基因ID
- 2891
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NCBI登录号
- NP_000817
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UniProt
- P42262
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途径
- PI3K-Akt Signaling
抗原
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