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GRIA2 抗体 (C-Term)

This anti-GRIA2 antibody is a 兔 多克隆 antibody detecting GRIA2 in WB. Suitable for 人, 大鼠, 小鼠, 斑马鱼 和 小鸡.
产品编号 ABIN372655
发货至: 中国

Quick Overview for GRIA2 抗体 (C-Term) (ABIN372655)

抗原

See all GRIA2 抗体
GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

适用

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人, 大鼠, 小鼠, 斑马鱼, 小鸡

宿主

  • 91
  • 26
  • 1

克隆类型

  • 79
  • 39
多克隆

标记

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This GRIA2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 28
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    C-Term

    特异性

    This antibody is specific for the ~100k GluR2/3 protein.

    交叉反应 (详细)

    Species reactivity (expected):Chicken, Human, Mouse and Zebrafish.
    Species reactivity (tested):Rat.
    Also reacts to: GLUR3

    纯化方法

    Affinity Chromatography.

    免疫原

    Peptide corresponding to amino acid residues from the C-terminal region of rat GluR2/3.

    亚型

    IgG
  • 应用备注

    Western blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原

    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

    别名

    Glutamate Receptor 2 / GLUR2

    背景

    The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003,Seidenman et al., 2003,Chung et al., 2003,Yan et al., 2002).Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic

    基因ID

    2891

    NCBI登录号

    NP_000817

    UniProt

    P42262

    途径

    PI3K-Akt Signaling
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