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GFAP 抗体

GFAP 适用: 人, 大鼠, 小鼠 WB, IF, IHC (fro) 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN372651
发货至: 中国
  • 抗原 See all GFAP 抗体
    GFAP (Glial Fibrillary Acidic Protein (GFAP))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 184
    • 139
    • 11
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    小鸡
    克隆类型
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    多克隆
    标记
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    This GFAP antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Specific for the ~50 kDa GFAP protein. A lower band at ~45 kDa is a proteolytic fragment derived from the GFAP molecule.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat.
    纯化方法
    Ig Fraction
    免疫原
    Recombinant and purified Bovine GFAP.
    亚型
    IgY
    Top Product
    Discover our top product GFAP Primary Antibody
  • 应用备注
    Western blot: 1/10,000. Immunofluorescence: 1/1,000. Immunohistochemitsry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    GFAP (Glial Fibrillary Acidic Protein (GFAP))
    别名
    GFAP (GFAP 产品)
    别名
    GFAP antibody, AI836096 antibody, cb345 antibody, etID36982.3 antibody, gfapl antibody, wu:fb34h11 antibody, wu:fk42c12 antibody, xx:af506734 antibody, zgc:110485 antibody, glial fibrillary acidic protein antibody, GFAP antibody, LOC100136168 antibody, gfap antibody, Gfap antibody
    背景
    Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques (1). It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers (2).Synonyms: Glial Fibrillary Acidic Protein
    基因ID
    24387
    NCBI登录号
    NP_058705
    UniProt
    P47819
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