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GABBR1 抗体 (pSer923)
GABBR1
适用: 人, 大鼠, 小鼠, Cow, Non-Human Primate
WB
宿主: 兔
Polyclonal
unconjugated
GABBR1抗体详情
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抗原
See all GABBR1 抗体
GABBR1
(gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
抗原表位
All epitopes for GABBR1 抗体
pSer923
适用
All reactivities for GABBR1 抗体
人, 大鼠, 小鼠, Cow, Non-Human Primate
宿主
All hosts for GABBR1 抗体
兔
克隆类型
All clonalities for GABBR1 抗体
多克隆
标记
All conjugates for GABBR1 抗体
This GABBR1 antibody is un-conjugated
应用范围
All applications for GABBR1 抗体
Western Blotting (WB)
特异性
Specific for ~102k GABAB R1 phosphorylated at Ser923. Immunolabeling of the GABAB R1 band is completely blocked by lambda-phosphatase treatment.
交叉反应 (详细)
Species reactivity (expected):Human, Bovine, Mouse and non-Human Primates. Species reactivity (tested):Rat.
纯化方法
Sequential Chromatography on phospho- and dephospho-peptide affinity columns.
免疫原
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser923 of GABAB R1
亚型
IgG
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Alternatives
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使用细节
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应用备注
Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Store the antibody undiluted (in aliquots) at-20 °C.
GABBR1目标详情
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抗原
GABBR1
(gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
别名
GABBR1 (GABBR1 产品 )
别名
GABABR1 antibody, GABBR1-3 antibody, GB1 antibody, GPRC3A antibody, dJ271M21.1.1 antibody, dJ271M21.1.2 antibody, gabbr1 antibody, GABBR1 antibody, GABA(B)R1 antibody, GABAB1 antibody, GABAbR1 antibody, bM573K1.1 antibody, gamma-aminobutyric acid type B receptor subunit 1 antibody, gamma-aminobutyric acid (GABA) B receptor, 1a antibody, gamma-aminobutyric acid (GABA) B receptor, 1 antibody, GABBR1 antibody, gabbr1a antibody, gabbr1 antibody, Gabbr1 antibody
背景
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling (Couve et al., 2004). Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.Synonyms: GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1, Gb1
基因ID
81657
NCBI登录号
NP_112290
UniProt
Q9Z0U4
途径
Positive Regulation of Peptide Hormone Secretion , cAMP Metabolic Process
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