GABRG2 抗体 (pSer327)
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- 抗原 See all GABRG2 抗体
- GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
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抗原表位
- pSer327
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 小鸡, Non-Human Primate
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABRG2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for ~45k GABAA Receptor Gamma2 subunit phosphorylated at Ser327. Immunolabeling of the GABAA band is completely blocked by Lambda-phosphatase treatment.
- 交叉反应 （详细）
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Species reactivity (expected):Human, Bovine, Canine, Chicken, Mouse and non-Human Primates.
Species reactivity (tested):Rat. - 纯化方法
- Sequential Chromatography on phospho- and dephospho-peptide affinity columns.
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser327 of the GABAA Receptor, Gamma2 subunit.
- 亚型
- IgG
- Top Product
- Discover our top product GABRG2 Primary Antibody
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anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (pSer327) antibody
GABRG2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 41-140) antibodyGABRG2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (N-Term) antibodyGABRG2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 170-270) antibodyGABRG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 198-224) antibodyGABRG2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB23939 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) antibodyGABRG2 适用: 人, 小鼠, 大鼠 ICC, IP 宿主: 小鼠 Monoclonal 331A12 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 198-224) antibodyGABRG2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 42-108) antibodyGABRG2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 61-110) antibodyGABRG2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, Pig, 马, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (AA 334-383) antibodyGABRG2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, Pig, 马, 豚鼠, 小鸡, 猴, Bat, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
- 别名
- GABRG2 (GABRG2 产品)
- 别名
- cae2 antibody, eca2 antibody, gabrg1 antibody, gefsp3 antibody, si:ch211-145n14.1 antibody, CAE2 antibody, ECA2 antibody, GEFSP3 antibody, GABAA-R antibody, Gabrg-2 antibody, gamma2 antibody, gamma-aminobutyric acid type A receptor gamma2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, gamma 2 antibody, gamma-aminobutyric acid type A receptor gamma 2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 antibody, GABRG2 antibody, gabrg2 antibody, Gabrg2 antibody
- 背景
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six Alpha's, four Beta's and four Gamma's, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990, Whiting et al., 1999, Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for Alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a Gamma-subunit is required for benzodiazepine modulation. It has recently been suggested that PKC-epsilon regulates the sensitivity of GABAA Alpha1/Beta2/Gamma2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of Gamma2 (Qi et al., 2007)Synonyms: GABA A Receptor subunit gamma-2, GABRG-2, Gamma-aminobutyric acid receptor subunit gamma-2
- 基因ID
- 29709
- NCBI登录号
- NP_899156
- UniProt
- P18508
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