GABRA3 抗体 (N-Term)
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- 抗原 See all GABRA3 抗体
- GABRA3 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 犬, Cow, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABRA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Specific for the ~51k Alpha-3 subunit of the GABAA receptor in Western blots. Labeling is absent in Alpha-3 subunit knockout animals.
- 交叉反应 （详细）
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Species reactivity (expected):Human, Bovine, Canine, Zebrafish and non-Human Primates.
Species reactivity (tested):Rat and Mouse. - 纯化方法
- Affinity Chromatography.
- 免疫原
- Fusion protein from N-terminal region of the Alpha-3 subunit of rat GABAA Receptor.
- 亚型
- IgG
- Top Product
- Discover our top product GABRA3 Primary Antibody
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anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) antibody
GABRA3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) antibodyGABRA3 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (N-Term) antibodyGABRA3 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (AA 29-43) antibodyGABRA3 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (AA 480-492) antibodyGABRA3 适用: 人, 大鼠, 小鼠, Cow, 兔, 马, 猴, Bat, Hamster IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (C-Term) antibodyGABRA3 适用: 人, 兔, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (N-Term) antibodyGABRA3 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (Middle Region) antibodyGABRA3 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (AA 29-43), (Extracellular), (N-Term) antibodyGABRA3 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF, IP, LCI 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) antibodyGABRA3 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- GABRA3 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3))
- 别名
- GABRA3 (GABRA3 产品)
- 别名
- GABRA3 antibody, Gabra-3 antibody, si:ch211-113k9.1 antibody, gamma-aminobutyric acid type A receptor alpha3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 3 antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 antibody, gamma-aminobutyric acid receptor subunit alpha-3 antibody, GABRA3 antibody, gabra3 antibody, Gabra3 antibody, LOC100653496 antibody
- 背景
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six Alpha's, four Beta's and four Gamma's, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990, Whiting et al., 1999, Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for Alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a Gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different Alpha-subunits of the receptor (McKernan et al., 2000, Mehta and Ticku, 1998, Ogris et al., 2004, Pöltl et al., 2003).Synonyms: GABA A Receptor subunit alpha-3, GABRA-3, Gamma-aminobutyric acid receptor subunit alpha-3
- 基因ID
- 24947
- NCBI登录号
- NP_058765
- UniProt
- P20236
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