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Dynamin 1 抗体 (pSer778)

DNM1 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡 WB 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN372617
发货至: 中国
  • 抗原 See all Dynamin 1 (DNM1) 抗体
    Dynamin 1 (DNM1)
    抗原表位
    • 31
    • 31
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer778
    适用
    • 106
    • 49
    • 46
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 小鸡
    宿主
    • 99
    • 9
    • 2
    绵羊
    克隆类型
    • 107
    • 4
    多克隆
    标记
    • 50
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Dynamin 1 antibody is un-conjugated
    应用范围
    • 88
    • 39
    • 39
    • 37
    • 20
    • 14
    • 13
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Specific for the ~95k dynamin protein phosphorylated at Ser778. This antibody labels the purified protein phosphorylated in vitro by CDK5 but not by PKC. Does not cross react with other purified substrates of CDK5 (e.g. Amphiphysin and Synapsin). Immunolabeling is blocked by lambda-phosphatase treatment.
    交叉反应 (详细)
    Species reactivity (expected):Human, Bovine, Canine, Chicken and Mouse.
    Species reactivity (tested):Rat.
    纯化方法
    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
    免疫原
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser778 of rat Dynamin.
    亚型
    IgG
    Top Product
    Discover our top product DNM1 Primary Antibody
  • 应用备注
    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    Dynamin 1 (DNM1)
    别名
    Dynamin-1 (DNM1 产品)
    别名
    DNM antibody, Dnm antibody, AI838169 antibody, Ftfl antibody, mKIAA4093 antibody, dnm antibody, DNM1 antibody, Dnm1 antibody, dnm1 antibody, si:dkey-246l19.2 antibody, dynamin 1 antibody, dynamin-1 antibody, dynamin 1a antibody, DNM1 antibody, Dnm1 antibody, BACOIKO008_37 antibody, PTRG_07818 antibody, PTRG_08097 antibody, dnm1 antibody, LOC100168088 antibody, LOC100199205 antibody, dnm1a antibody
    背景
    Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001, Graham et al., 2002, Tsuboi et al., 2002). Cyclin dependent protein kinase 5 phosphorylates Dynamin at Ser774 and Ser778 that are the phosphorylation sites on Dynamin phosphorylated in vivo (Tan et al., 2003). Phosphorylation of these sites on Dynamin is thought to play a key role in synaptic vesicle trafficking.Synonyms: DNM, DNM1
    基因ID
    140694
    NCBI登录号
    NP_542420
    UniProt
    P21575
    途径
    Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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