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DDC 抗体

DDC 适用: 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN372608
发货至: 中国
  • 抗原 See all DDC 抗体
    DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
    适用
    • 70
    • 42
    • 34
    • 10
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    • 1
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    大鼠, Cow
    宿主
    • 61
    • 9
    • 2
    • 2
    克隆类型
    • 59
    • 15
    多克隆
    标记
    • 38
    • 6
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    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
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    This DDC antibody is un-conjugated
    应用范围
    • 59
    • 29
    • 26
    • 16
    • 13
    • 13
    • 13
    • 10
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    • 4
    • 3
    • 1
    Western Blotting (WB)
    特异性
    Specific for the ~55k DDC protein.
    交叉反应 (详细)
    Species reactivity (expected):Bovine.
    Species reactivity (tested):Rat.
    纯化方法
    Affinity Chromatography using an AminoLink® Plus column matrix to which purified recombinant Bovine DDC was coupled.
    免疫原
    SDS denatured, recombinant bovine aromatic DOPA decarboxylase (DDC) expressed in E. coli and purified from inclusion bodies.
    亚型
    IgG
    Top Product
    Discover our top product DDC Primary Antibody
  • 应用备注
    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原
    DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
    别名
    AADC / DDC (DDC 产品)
    别名
    AADC antibody, wu:fa56d05 antibody, wu:fd59h03 antibody, wu:fk20h01 antibody, zgc:65801 antibody, zgc:76929 antibody, Ddc antibody, DdcDv antibody, Dvir\\GJ17995 antibody, GJ17995 antibody, dvir_GLEANR_2561 antibody, Aadc antibody, 5-HT antibody, CG10697 antibody, DDC antibody, DdcDm antibody, Dmel\\CG10697 antibody, ddc antibody, fDDC antibody, l(2)37Bl antibody, l(2)37Ch antibody, l(2)k02104 antibody, dopa decarboxylase antibody, Dopa-decarboxylase antibody, dopa decarboxylase (aromatic L-amino acid decarboxylase) antibody, Dopa decarboxylase antibody, dopa decarboxylase L homeolog antibody, DDC antibody, ddc antibody, Ddc antibody, Dvir\Ddc antibody, ddc.L antibody
    背景
    DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.Synonyms: Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase
    基因ID
    24311
    NCBI登录号
    NP_036677
    UniProt
    P14173
    途径
    Dopaminergic Neurogenesis
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