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CDK1 抗体 (pTyr15)

The 兔 多克隆 anti-CDK1 antibody is suitable to detect CDK1 in samples from 人, 小鼠, 大鼠, 非洲爪蟾 和 斑马鱼. It has been validated for WB.
产品编号 ABIN372596
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDK1 抗体 (pTyr15) (ABIN372596)

抗原

See all CDK1 抗体
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

适用

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人, 小鼠, 大鼠, 非洲爪蟾, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This CDK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pTyr15

    特异性

    Specific for the ~38k CDC2 protein phosphorylated at Tyr15. Immunolabeling is blocked by the lambda-phosphatase treatment.

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat and Zebrafish.
    Species reactivity (tested):Human and Xenopus.

    纯化方法

    Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

    免疫原

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Tyr15 of rat CDC2.

    亚型

    IgG
  • 应用备注

    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at-20 °C.
  • 抗原

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    别名

    CDK1

    背景

    Cdc2 is a highly conserved protein serine kinase that plays a key role in regulation of the cell cycle (Maller, 1991). The ability of cdc2 to exercise control over the cell cycle is dependent upon the phosphorylation of Tyr15 in cdc2 (Nakamizo et al., 2002). cdc2 expression in brain has been linked to both neurogenesis and apoptosis (Konishi and Bonni, 2003, Dranovsky et al., 2001, Okano et al., 1996).Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase

    基因ID

    983

    NCBI登录号

    NP_001777

    UniProt

    P06493

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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