IFIH1 抗体 (C-Term)
-
- 抗原 See all IFIH1 抗体
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This IFIH1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody recognizes Melanoma Differentiation Associated Protein-5 (MDA5/IFIH1).
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic peptide corresponding to 16 amino acids from near the carboxy terminus of human MDA5.
- 亚型
- IgG
- Top Product
- Discover our top product IFIH1 Primary Antibody
-
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-205) antibody
IFIH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (C-Term) antibodyIFIH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (N-Term) antibodyVerified IFIH1 适用: 人, 猴 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 700-1025) antibodyIFIH1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 1-221) antibodyIFIH1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 928-1023) antibodyIFIH1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (AA 612-661) antibodyIFIH1 适用: 人, 小鼠, 大鼠, Pig, Cow, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) antibodyIFIH1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Interferon Induced with Helicase C Domain 1 (IFIH1) antibodyIFIH1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
-
- 抗原
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
- 别名
- Helicard (IFIH1 产品)
- 别名
- MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody
- 背景
- DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. It is believed that MDA-5 may function to promote message degradation by specific RNases. It also seems to possess growth inhibition properties. The interaction of MDA5 with double stranded RNA can lead to induction of IFN required for the the innate immune response against viruses.Synonyms: Helicase with 2 CARD domains, IFIH1, Interferon-induced helicase C domain-containing protein 1, MDA5, Melanoma differentiation-associated protein 5, Murabutide down-regulated protein, RH116, RNA helicase-DEAD box protein 116
- 基因ID
- 64135
- NCBI登录号
- NP_071451
- UniProt
- Q9BYX4
- 途径
- Activation of Innate immune Response
-
