TMEM123 抗体 (AA 173-188)
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Quick Overview for TMEM123 抗体 (AA 173-188) (ABIN372449)
抗原
See all TMEM123 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 173-188
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序列
- SRRGIRYRTI DEHDAI
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特异性
- This antibody recognizes TMEM123/Porimin.
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交叉反应 (详细)
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Species reactivity (expected):Bovine (Cow), Chicken, Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Protein G Chromatography.
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免疫原
- Synthetic peptide corresponding to amino acids 173-188 of human Porimin.
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亚型
- IgG
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应用备注
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Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- TMEM123 (Transmembrane Protein 123 (TMEM123))
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别名
- TMEM123 / Porimin
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背景
- Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110- kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.Synonyms: KCT-3, KCT3, Keratinocytes-associated transmembrane protein 3, PSEC0111, Pro-oncosis receptor inducing membrane injury, Transmembrane protein 123
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基因ID
- 114908
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NCBI登录号
- NP_443164
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UniProt
- Q8N131
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途径
- Regulation of Cell Size
抗原
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