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TMEM123 抗体 (AA 173-188)

This anti-TMEM123 antibody is a 兔 多克隆 antibody detecting TMEM123 in WB 和 IHC (p). Suitable for 人, 小鼠, 大鼠, Cow 和 小鸡.
产品编号 ABIN372449
发货至: 中国

Quick Overview for TMEM123 抗体 (AA 173-188) (ABIN372449)

抗原

See all TMEM123 抗体
TMEM123 (Transmembrane Protein 123 (TMEM123))

适用

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人, 小鼠, 大鼠, Cow, 小鸡

宿主

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克隆类型

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多克隆

标记

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This TMEM123 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
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    AA 173-188

    序列

    SRRGIRYRTI DEHDAI

    特异性

    This antibody recognizes TMEM123/Porimin.

    交叉反应 (详细)

    Species reactivity (expected):Bovine (Cow), Chicken, Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Protein G Chromatography.

    免疫原

    Synthetic peptide corresponding to amino acids 173-188 of human Porimin.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    TMEM123 (Transmembrane Protein 123 (TMEM123))

    别名

    TMEM123 / Porimin

    背景

    Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110- kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.Synonyms: KCT-3, KCT3, Keratinocytes-associated transmembrane protein 3, PSEC0111, Pro-oncosis receptor inducing membrane injury, Transmembrane protein 123

    基因ID

    114908

    NCBI登录号

    NP_443164

    UniProt

    Q8N131

    途径

    Regulation of Cell Size
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