TLX1 抗体 (AA 300-330)
Our Local Distributor
北京 101111
Quick Overview for TLX1 抗体 (AA 300-330) (ABIN372448)
抗原
See all TLX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 300-330
-
特异性
- This antibody recognizes Homeobox Protein Hox-11 (TLX1).
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Protein G Chromatography.
-
免疫原
- Synthetic peptide corresponding to a portion of amino acids 300-330 of human HOX11.
-
亚型
- IgG
-
-
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 300-330), (AA 306-318) antibody
TLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, Bat, 猴, 小鸡, 马, Hamster WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 163-191) antibodyTLX1 适用: 小鼠, 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 144-193) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 猴, 小鸡, 马, 斑马鱼, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (C-Term) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 猴, 小鸡, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 1-190) antibodyTLX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (N-Term) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (AA 163-191) antibodyTLX1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB31060 unconjugated
anti-T-Cell Leukemia Homeobox 1 (TLX1) (N-Term) antibodyTLX1 适用: 小鼠, 人, 大鼠, Cow, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
-
别名
- TLX1
-
背景
- HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35,q24) or t(10:14)(q24,qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.Synonyms: HOX11, Hox-11, T-cell leukemia homeobox protein 1, T-cell leukemia/lymphoma protein 3, TCL-3, TCL3, TLX-1
-
基因ID
- 3195
-
NCBI登录号
- NP_005512
-
UniProt
- P31314
抗原
-
