SIRT7 抗体 (AA 35-51, AA 361-377)
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Quick Overview for SIRT7 抗体 (AA 35-51, AA 361-377) (ABIN372439)
抗原
See all SIRT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-51, AA 361-377
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特异性
- This antibody recognizes Sirtuin Type 7 (SIRT7).
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纯化方法
- Protein G Chromatography.
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免疫原
- A mixture of synthetic peptides corresponding to amino acids 35-51 and 361-377 of human SIRT7.
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亚型
- IgG
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应用备注
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Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- SIRT7 (Sirtuin 7 (SIRT7))
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别名
- SIRT7
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背景
- SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.Synonyms: NAD-dependent deacetylase sirtuin-7, S.cerevisiae, SIR2-like protein 7, SIR2L7, SIRT-7, homolog) 7, sirtuin (silent mating type information regulation 2, sirtuin 7, sirtuin type 7, sirtuin-7
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基因ID
- 51547
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NCBI登录号
- NP_057622
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UniProt
- Q9NRC8
抗原
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