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SIRT7 抗体 (AA 35-51, AA 361-377)

This 兔 多克隆 antibody specifically detects SIRT7 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN372439
发货至: 中国
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Quick Overview for SIRT7 抗体 (AA 35-51, AA 361-377) (ABIN372439)

抗原

See all SIRT7 抗体
SIRT7 (Sirtuin 7 (SIRT7))

适用

  • 50
  • 36
  • 28
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1

宿主

  • 66
  • 6
  • 2

克隆类型

  • 70
  • 4
多克隆

标记

  • 37
  • 8
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT7 antibody is un-conjugated

应用范围

  • 59
  • 28
  • 26
  • 16
  • 13
  • 13
  • 10
  • 8
  • 6
  • 5
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-51, AA 361-377

    特异性

    This antibody recognizes Sirtuin Type 7 (SIRT7).

    纯化方法

    Protein G Chromatography.

    免疫原

    A mixture of synthetic peptides corresponding to amino acids 35-51 and 361-377 of human SIRT7.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western blot: 1-3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    SIRT7 (Sirtuin 7 (SIRT7))

    别名

    SIRT7

    背景

    SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.Synonyms: NAD-dependent deacetylase sirtuin-7, S.cerevisiae, SIR2-like protein 7, SIR2L7, SIRT-7, homolog) 7, sirtuin (silent mating type information regulation 2, sirtuin 7, sirtuin type 7, sirtuin-7

    基因ID

    51547

    NCBI登录号

    NP_057622

    UniProt

    Q9NRC8
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