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AQP2 抗体 (N-Term)

This anti-AQP2 antibody is a 兔 多克隆 antibody detecting AQP2 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN372293
发货至: 中国

Quick Overview for AQP2 抗体 (N-Term) (ABIN372293)

抗原

See all AQP2 抗体
AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This AQP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    N-Term

    特异性

    This antibody recognizes Aquaporin 2 (N-term).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic peptide corresponding to N-terminal residues of Human Aquaporin 2.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL. ELISA: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

    别名

    Aquaporin-2

    背景

    Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins. Aquaporin 0, and Aquaporin 1 have been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80 % of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal dominant cataract. The lens opacity mutation is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains. The N and C terminus are predicted to be cytoplasmic. Aquaporin 2 is located in the collecting tubule.Synonyms: ADH water channel, AQP-CD, AQP2, Aquaporin-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct

    分子量

    29 kDa.

    基因ID

    359

    NCBI登录号

    NP_000477

    UniProt

    P41181

    途径

    Response to Water Deprivation
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