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TUBB3 抗体

The 小鼠 单克隆 anti-TUBB3 antibody (Clone AA10) (ABIN371847) specifically detects TUBB3 in WB 和 IHC (p). The antibody is reactive with 大鼠 samples.
产品编号 ABIN371847
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TUBB3 抗体 (ABIN371847)

抗原

See all TUBB3 抗体
TUBB3 (Tubulin, beta 3 (TUBB3))

适用

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大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This TUBB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

AA10
  • 特异性

    AM08272PU-N is specific for the ~55 kDa beta III Tubulin protein. Note: This clone is similar to the Monoclonal antibody Tuj1.

    交叉反应 (详细)

    Species reactivity (tested):Rat.

    产品特性

    Synonyms: Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4

    纯化方法

    Protein G Chromatography.

    免疫原

    Synthetic peptide corresponding to beta III tubulin.

    亚型

    IgG
  • 应用备注

    Western Blot: 1/10,000. Immunohistochemistry: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    TUBB3 (Tubulin, beta 3 (TUBB3))

    别名

    TUBB3 / TUBB4

    背景

    Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

    基因ID

    246118

    UniProt

    Q4QRB4

    途径

    Microtubule Dynamics, M Phase
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