TUBB3 抗体
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北京 101111
Quick Overview for TUBB3 抗体 (ABIN371847)
抗原
See all TUBB3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- AM08272PU-N is specific for the ~55 kDa beta III Tubulin protein. Note: This clone is similar to the Monoclonal antibody Tuj1.
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交叉反应 (详细)
- Species reactivity (tested):Rat.
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产品特性
- Synonyms: Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4
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纯化方法
- Protein G Chromatography.
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免疫原
- Synthetic peptide corresponding to beta III tubulin.
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亚型
- IgG
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应用备注
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Western Blot: 1/10,000. Immunohistochemistry: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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储存条件
- -20 °C
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储存方法
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Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TUBB3 (Tubulin, beta 3 (TUBB3))
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别名
- TUBB3 / TUBB4
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背景
- Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III
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基因ID
- 246118
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UniProt
- Q4QRB4
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途径
- Microtubule Dynamics, M Phase
抗原
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