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THRB 抗体 (N-Term)

The 小鼠 单克隆 anti-THRB antibody is suitable to detect THRB in samples from 人. It has been validated for WB.
产品编号 ABIN371846
发货至: 中国
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Quick Overview for THRB 抗体 (N-Term) (ABIN371846)

抗原

See all THRB 抗体
THRB (Thyroid Hormone Receptor, beta (THRB))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This THRB antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

2386
  • 抗原表位

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    N-Term

    特异性

    This antibody is specific for the ~58k THR-beta protein.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: Thyroid hormone receptor beta, THR1, NR1A2, Nuclear receptor subfamily 1 group A member2

    纯化方法

    Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

    免疫原

    Peptide corresponding to amino acid residues from the N-terminal region of human thyroidhormone receptor, beta-isotype.

    亚型

    IgG1
  • 应用备注

    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    THRB (Thyroid Hormone Receptor, beta (THRB))

    别名

    THRB / ERBA2

    背景

    Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005, Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TR-alpha1, TR-alpha2, TR-beta1 and TR-beta2. TR-alpha1, TR-beta1 and TR-beta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).Synonyms: NR1A2, Nuclear receptor subfamily 1 group A member 2, THR1, Thyroid hormone receptor beta

    基因ID

    7068

    UniProt

    P10828

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
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