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Retinoid X Receptor beta 抗体

This 小鼠 单克隆 antibody specifically detects Retinoid X Receptor beta in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN371839
发货至: 中国
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Quick Overview for Retinoid X Receptor beta 抗体 (ABIN371839)

抗原

See all Retinoid X Receptor beta (RXRB) 抗体
Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

适用

  • 48
  • 30
  • 29
  • 9
  • 8
  • 7
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 40
  • 8
  • 1
小鼠

克隆类型

  • 41
  • 8
单克隆

标记

  • 32
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Retinoid X Receptor beta antibody is un-conjugated

应用范围

  • 49
  • 16
  • 11
  • 7
  • 5
  • 4
  • 4
  • 1
  • 1
Western Blotting (WB)

克隆位点

147
  • 特异性

    This antibody is specific for the ~48k RAR-beta isotype.

    交叉反应 (详细)

    Species reactivity (expected):Human.
    Species reactivity (tested):Mouse and Rat

    产品特性

    Synonyms: NR2B2, H-2RIIBP, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta, Nuclearreceptor subfamily 2 group B member 2, Nuclear Receptor Coregulator 1

    纯化方法

    Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

    免疫原

    Hinge peptide corresponding to amino acids from Human, Mouse and Rat retinoid Xreceptor, beta-isotype.

    亚型

    IgG1
  • 应用备注

    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

    别名

    RXR-beta / RXRB

    背景

    Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: H-2RIIBP, NR2B2, Nuclear Receptor Coregulator 1, Nuclear receptor subfamily 2 group B member 2, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta

    基因ID

    6257

    UniProt

    P28702

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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