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Retinoic Acid Receptor alpha 抗体 (N-Term)

This anti-Retinoic Acid Receptor alpha antibody is a 小鼠 单克隆 antibody detecting Retinoic Acid Receptor alpha in WB. Suitable for 人, 小鼠, Cow 和 犬.
产品编号 ABIN371837
发货至: 中国

Quick Overview for Retinoic Acid Receptor alpha 抗体 (N-Term) (ABIN371837)

抗原

See all Retinoic Acid Receptor alpha (RARA) 抗体
Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

适用

  • 90
  • 42
  • 39
  • 4
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  • 2
  • 1
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  • 1
人, 小鼠, Cow, 犬

宿主

  • 79
  • 19
  • 1
小鼠

克隆类型

  • 71
  • 28
单克隆

标记

  • 62
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Retinoic Acid Receptor alpha antibody is un-conjugated

应用范围

  • 65
  • 42
  • 40
  • 19
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  • 14
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  • 13
  • 13
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
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  • 1
  • 1
Western Blotting (WB)

克隆位点

763
  • 抗原表位

    • 15
    • 11
    • 8
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody is specific for the ~48k RAR-alpha isotype.

    交叉反应 (详细)

    Species reactivity (expected):Bovine, Canine (Dog) and Mouse.
    Species reactivity (tested):Human.

    产品特性

    Synonyms: NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1

    纯化方法

    Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.

    免疫原

    Peptide corresponding to amino acid residues from the N-terminal region of humanretinoic acid receptor, alpha-isotype.

    亚型

    IgG1
  • 应用备注

    Western Blot: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

    别名

    RAR-alpha / RARA

    背景

    Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: NR1B1, Nuclear receptor subfamily 1 group B member 1, Retinoic acid receptor alpha

    基因ID

    5914

    UniProt

    P10276

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins
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