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ITGA2 抗体

The 小鼠 单克隆 anti-ITGA2 antibody is suitable to detect ITGA2 in samples from 人. It has been validated for FACS 和 IP.
产品编号 ABIN371516
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ITGA2 抗体 (ABIN371516)

抗原

See all ITGA2 抗体
ITGA2 (Integrin alpha 2 (ITGA2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGA2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

HAS-4
  • 特异性

    This antibody recognizes CD49b (Mr 200-210 kDa).

    产品特性

    Synonyms: Integrin alpha-2, ITGA-2, VLA-2 alpha, VLA2, GPIa, Collagen Receptor, Platelet membraneglycoprotein Ia, CD49 antigen-like family member B

    纯化方法

    Purified

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: Identification and enumeration of CD49b+ cells (< / = 1 μg/10^6 cells). Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    ITGA2 (Integrin alpha 2 (ITGA2))

    别名

    CD49b / ITGA2

    背景

    CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha-2 chain. CD49b associates noncovalently with CD29, the integrin beta-1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg++ dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2

    基因ID

    3673

    UniProt

    P17301

    途径

    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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