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TCR gamma/delta 抗体

The 小鼠 单克隆 anti-TCR gamma/delta antibody is suitable to detect TCR gamma/delta in samples from 小鸡. It has been validated for FACS, IP, IHC (fro) 和 Func.
产品编号 ABIN371342
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TCR gamma/delta 抗体 (ABIN371342)

抗原

TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

适用

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小鸡

宿主

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小鼠

克隆类型

  • 61
单克隆

标记

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This TCR gamma/delta antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

TCR1
  • 产品特性

    Synonyms: TCRG, TCRD, T-Cell Receptor gamma, T-Cell Receptor delta, T-Cell Receptor gamma delta,T-cell surface glycoprotein CD3 gamma/delta, T-cell receptor T3 gamma/delta

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    Flow Cytometry. (Ref.1-3)Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). (Ref.5)Immunoprecipitation. (Ref.1-3)In ovo depletion of gamma delta T cells. (Ref.6,7)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

    别名

    T Cell Receptor / TCR gamma/delta

    背景

    T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. Unlike human and mouse, in which gamma/delta cells comprise a minor subset of T lymphocytes in the circulation, the chicken has a relatively large subset of gamma/delta T cells. The frequency of TCR gamma/delta cells is usually 20-25 % of the total blood T cells, but may reach approximately 50 % in chickens of 6 months of age. The majority of TCRgamma/delta+ cells in the thymus and blood are CD4-CD8-, although a small subset of them may express CD8 or CD4 coreceptors. However, when the TCRgamma/delta+ cells migrate into the spleen and intestine, most of them begin to express CD8. Although the biological function of gamma/delta T cells is unclear, they are clearly capable of cytotoxic activity in vitro. The CD8+ gamma/delta T cells may also be involved in down-regulation of the immune response. They cannot, however, induce a graft-vs-host (GVH) reactions.Synonyms: T-Cell Receptor delta, T-Cell Receptor gamma, T-Cell Receptor gamma delta, TCR delta, TCR gamma, TCRD, TCRG
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