MHC Class I H-2Db 抗体 (PE)
Our Local Distributor
北京 101111
Quick Overview for MHC Class I H-2Db 抗体 (PE) (ABIN371176)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody recognizes the alpha 3 domain of H-2Db class I MHC antigen. It cross-reacts with the alpha 3 domain of H-2Ld, H-2Dq and H-2Lq, but not H-2Kd or H-2Dd. Reactivity with haplotypes k, f, p, r, and s has not been observed. Customer feedback: Clone 27-11-13S does not cross-react with human cells.
-
产品特性
- Synonyms: H-2D(B), H2-D1, H-2 class I histocompatibility antigen, D-B alpha chain
-
免疫原
- C3H alphaBDF1 splenocytes. (Ref. 1)
-
亚型
- IgG2a
-
-
-
-
应用备注
-
Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.1-3)Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- MHC Class I H-2Db
-
别名
- MHC Class I H-2 Db
-
背景
- In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant beta 2 Microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.Synonyms: D-B alpha chain, H-2 class I histocompatibility antigen, H-2D(B), H2-D1
-
基因ID
- 14964
-
UniProt
- P01899
抗原
-