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MHC Class I H-2Db 抗体 (PE)

This 小鼠 单克隆 antibody specifically detects MHC Class I H-2Db in FACS. It exhibits reactivity toward 小鼠.
产品编号 ABIN371176
发货至: 中国
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Quick Overview for MHC Class I H-2Db 抗体 (PE) (ABIN371176)

抗原

MHC Class I H-2Db

适用

小鼠

宿主

  • 9
  • 2
小鼠

克隆类型

  • 11
单克隆

标记

  • 5
  • 2
  • 2
  • 2
PE

应用范围

  • 9
  • 7
  • 4
  • 4
  • 2
Flow Cytometry (FACS)

克隆位点

27-11-13S
  • 特异性

    This antibody recognizes the alpha 3 domain of H-2Db class I MHC antigen. It cross-reacts with the alpha 3 domain of H-2Ld, H-2Dq and H-2Lq, but not H-2Kd or H-2Dd. Reactivity with haplotypes k, f, p, r, and s has not been observed. Customer feedback: Clone 27-11-13S does not cross-react with human cells.

    产品特性

    Synonyms: H-2D(B), H2-D1, H-2 class I histocompatibility antigen, D-B alpha chain

    免疫原

    C3H alphaBDF1 splenocytes. (Ref. 1)

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.1-3)Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    MHC Class I H-2Db

    别名

    MHC Class I H-2 Db

    背景

    In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant beta 2 Microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.Synonyms: D-B alpha chain, H-2 class I histocompatibility antigen, H-2D(B), H2-D1

    基因ID

    14964

    UniProt

    P01899
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