MHC Class I H-2Db 抗体
The 小鼠 单克隆 anti-MHC Class I H-2Db antibody (Clone 27-11-13S) (ABIN371175) specifically detects MHC Class I H-2Db in FACS 和 CyTox.
The antibody is reactive with 小鼠 samples.
产品编号 ABIN371175
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for MHC Class I H-2Db 抗体 (ABIN371175)
抗原
MHC Class I H-2Db
适用
小鼠
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS), Cytotoxicity Test (CyTox)
克隆位点
27-11-13S
-
-
特异性
- This antibody recognizes the alpha 3 domain of H-2Db class I MHC antigen. It cross-reacts with the alpha 3 domain of H-2Ld, H-2Dq and H-2Lq, but not H-2Kd or H-2Dd. Reactivity with haplotypes k, f, p, r, and s has not been observed. Customer feedback: Clone 27-11-13S does not cross-react with human cells.
-
产品特性
- Synonyms: H-2D(B), H2-D1, H-2 class I histocompatibility antigen, D-B alpha chain
-
纯化方法
- Purified
-
免疫原
- C3H alphaBDF1 splenocytes. (Ref. 1)
-
亚型
- IgG2a
-
-
-
-
应用备注
-
Flow Cytometry. (Ref.1-3)Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). Complement-mediated cytotoxicity. (Ref.1,2)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
-
储存条件
- 4 °C/-20 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- MHC Class I H-2Db
-
别名
- MHC Class I H-2 Db
-
背景
- In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant beta 2 Microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.Synonyms: D-B alpha chain, H-2 class I histocompatibility antigen, H-2D(B), H2-D1
-
基因ID
- 14964
-
UniProt
- P01899
抗原
-
You are here:
