MHC Class II I-Ab 抗体
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Quick Overview for MHC Class II I-Ab 抗体 (ABIN371141)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain
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纯化方法
- Purified
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亚型
- IgG2b
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anti-MHC Class II I-Ab antibody
适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 25-9-3 unconjugated
anti-MHC Class II I-Ab antibody (PE)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 25-9-3 PE
anti-MHC Class II I-Ab antibody (Biotin)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 25-9-3 Biotin
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应用备注
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Flow Cytometry: < / = 1 μg/10^6 cells. Complement-dependent Cytotoxicity Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- MHC Class II I-Ab
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背景
- MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.Synonyms: H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1
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UniProt
- P18468
抗原
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