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TCR gamma/delta 抗体

This 仓鼠 单克隆 antibody specifically detects TCR gamma/delta in FACS, IP, IHC (fro) 和 Func. It exhibits reactivity toward 小鼠.
产品编号 ABIN371050
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TCR gamma/delta 抗体 (ABIN371050)

抗原

TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

适用

  • 24
  • 21
  • 9
  • 7
  • 6
  • 4
小鼠

宿主

  • 39
  • 13
  • 6
  • 2
  • 1
仓鼠

克隆类型

  • 61
单克隆

标记

  • 23
  • 12
  • 11
  • 9
  • 4
  • 1
  • 1
This TCR gamma/delta antibody is un-conjugated

应用范围

  • 61
  • 17
  • 14
  • 14
  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

UC7-13D5
  • 产品特性

    Synonyms: TCRG, TCRD, T-Cell Receptor gamma, T-Cell Receptor delta, T-Cell Receptor gamma delta

    内毒素水平

    Low Endotoxin

    亚型

    IgG
  • 应用备注

    Flow Cytometry. (Ref.4-7)Immunoprecipitation. (Ref.5)Immunohistochemistry on Frozen Sections. (Ref.8)In vitro Activation of gamma-delta TCR-bearing cells. (Ref.5)In vivo Depletion of gamma-delta TCR-expressing T cells. (Ref.5)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing no preservatives.

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquous) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

    别名

    T Cell Receptor / TCR gamma/delta

    背景

    T cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment, a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. The TCR gamma/delta heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. (Ref.1) It is expressed during thymopoiesis and on the small subpopulation of gamma/delta TCR expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gamma/delta+ and have limited receptor diversity. (Ref.1,2) The TCR gamma/delta heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation. (Ref.3)Synonyms: T-Cell Receptor delta, T-Cell Receptor gamma, T-Cell Receptor gamma delta, TCRD, TCRG
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