CD38 抗体 (Biotin)
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Quick Overview for CD38 抗体 (Biotin) (ABIN370930)
抗原
See all CD38 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific to CD38 (Mr. 42-46 kDa). Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. (Ref.1-8)
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产品特性
- Synonyms: cADPr hydrolase 1, T10, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1
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亚型
- IgG2a
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应用备注
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Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1-8)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CD38
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背景
- Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing Nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRalphabeta+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1
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基因ID
- 12494
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UniProt
- P56528
抗原
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