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CD19 抗体

This anti-CD19 antibody is a 小鼠 单克隆 antibody detecting CD19 in FACS 和 IP. Suitable for 小鼠.
产品编号 ABIN370860
发货至: 中国

Quick Overview for CD19 抗体 (ABIN370860)

抗原

See all CD19 抗体
CD19 (CD19 Molecule (CD19))

适用

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小鼠

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小鼠

克隆类型

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单克隆

标记

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This CD19 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

MB19-1
  • 特异性

    This antibody is specific to CD19 B cell differentiation antigen (Mr. 95 kDa)

    产品特性

    Synonyms: Leu-12, B-cell marker, Differentiation antigen CD19, B-lymphocyte surface antigen B4

    纯化方法

    Purified

    免疫原

    CD19+ mouse pre-B cell line, 300. 19. (Ref. 1)

    亚型

    IgA
  • 应用备注

    Flow Cytometry. (Ref.1-3)Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    背景

    CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e., B220+/CD43+/HSA+) through fully differentiated B cell stages. (Ref.1-7) Terminally differentiated plasma cells do not express CD19.1 In humans, the CD19 Molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. (Ref.3,4) All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. (Ref.1,7) Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. (Ref.7)Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12

    基因ID

    12478

    UniProt

    P25918

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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