HPV16 E7 抗体
Quick Overview for HPV16 E7 抗体 (ABIN363828)
抗原
See all HPV16 E7 (HPV-16 E7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. Does not cross-react with E7 protein of HPV-18.
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纯化方法
- Affinity purified
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免疫原
- Oncoprotein E7 from human papillomavirus 16.
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亚型
- IgG1
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anti-Human Papilloma Virus 16 E7 (HPV-16 E7) (Middle Region) antibody
HPV-16 E7 适用: Human Papillomavirus 16 (HPV-16) WB, IF (p), ELISA, FACS, IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Human Papilloma Virus 16 E7 (HPV-16 E7) antibodyHPV-16 E7 适用: Human Papillomavirus 16 (HPV-16) WB, ELISA 宿主: 小鼠 Monoclonal 3D6F1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human Papillomavirus
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.2, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
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别名
- HPV16 E7
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物质类
- Viral Protein
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背景
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Name/Gene ID: HPV16-E7
Synonyms: HPV16-E7 -
基因ID
- 1489079
抗原
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