PLTP 抗体
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北京 101111
Quick Overview for PLTP 抗体 (ABIN363330)
抗原
See all PLTP 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with PLTN from human and mouse
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纯化方法
- Antiserum
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免疫原
- A partial peptide of human PLTP
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 - IHC - P : 1/500 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- , Sodium azide 0.02 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C/-80 °C
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储存方法
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- PLTP (Phospholipid Transfer Protein (PLTP))
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背景
- PLTP (phospholipid transfer protein) belongs to lipid transfer/lipopolysaccharide-binding proteins (BPI/LBP) family and it is a monomeric sectered protein expressed ubiquitously with highest expression in liver, one of the major sites of lipoprotein production and degradation. PLTP converts HDL into larger and smaller particles, and play a key role in extracellular phospholipid transport as well as modulation of HDL particles. Plasma PLTP is also considered a nonspecific lipid transfer protein because, along with phospholipids, it can also transfer alpha-tocopherol, diacylglycerol, cerebroside, and lipopolysaccharides. PLTP deficient mice depicts lowered susceptibility for atherosclerosis, whereas, PLTP transgenic mice have more atherosclerosis. In humans, an increased PLTP activity been linked to several conditions including type I/II diabetes mellitus, metabolic syndrome, obesitas, increased risk of coronary artery disease and cardiovascular disease.
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途径
- Lipid Metabolism
抗原
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