HDAC4/HDAC5/HDAC9 抗体 (AA 244-248)
Quick Overview for HDAC4/HDAC5/HDAC9 抗体 (AA 244-248) (ABIN363088)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 244-248
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特异性
- The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody detects endogenous levels of total HDAC4/HDAC5/HDAC9 protein.
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免疫原
- Peptide sequence around AA 244-248, 257-261, 218-222 (T-A-S-E-P) derived from Human HDAC4, HDAC5, HDAC9. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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anti-HDAC4,HDAC5,HDAC9 antibody
适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HDAC4,HDAC5,HDAC9 (pSer220), (pSer246), (pSer259) antibody适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HDAC4,HDAC5,HDAC9 (Ser220), (Ser246), (Ser259) antibody适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HDAC4,HDAC5,HDAC9 (pSer220), (pSer246), (pSer259) antibody适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)
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别名
- HDAC4/HDAC5/HDAC9
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背景
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
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分子量
- 124 kDa
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NCBI登录号
- NP_055522, NP_001015
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UniProt
- Q9UKV0
抗原
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