GRIA2 抗体 (AA 878-882)
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Quick Overview for GRIA2 抗体 (AA 878-882) (ABIN362994)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 878-882
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特异性
- The antibody detects endogenous level of total Glutamate receptor 2 (Precursor) protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Peptide sequence around AA 878-882 (I-E-S-V-K) derived from Human Glutamate receptor 2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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应用备注
- Western blotting: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- Glutamate receptor 2 (Precursor)
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背景
- Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
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分子量
- 100 kDa
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NCBI登录号
- NP_000817
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UniProt
- P42262
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途径
- PI3K-Akt Signaling
抗原
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