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Synuclein 抗体 (AA 134-138)

SYU 适用: 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362982
发货至: 中国
  • 抗原 See all Synuclein (SYU) products
    Synuclein (SYU)
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 134-138
    适用
    • 18
    • 15
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    小鼠, 大鼠
    宿主
    • 16
    • 2
    克隆类型
    • 18
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Synuclein antibody is un-conjugated
    应用范围
    • 11
    • 8
    • 4
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    The antibody detects endogenous level of total a-Synuclein protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
    免疫原
    Peptide sequence around AA 134-138 (Q-D-Y-E-P) derived from Mouse a-Synuclein. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    亚型
    IgG
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunofluorescence: 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Zhong, Luo, Chen, Cai, Liu, Chen, Yao: "Expression and subcellular location of alpha-synuclein during mouse-embryonic development." in: Cellular and molecular neurobiology, Vol. 30, Issue 3, pp. 469-82, (2010) (PubMed).

  • 抗原
    Synuclein (SYU)
    别名
    Synuclein (SYU 产品)
    背景
    May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Takahashi T,
    分子量
    18 kDa
    NCBI登录号
    NP_001035
    UniProt
    P37840
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