Synuclein 抗体 (AA 134-138)
(1 reference)Quick Overview for Synuclein 抗体 (AA 134-138) (ABIN362982)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 134-138
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特异性
- The antibody detects endogenous level of total a-Synuclein protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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免疫原
- Peptide sequence around AA 134-138 (Q-D-Y-E-P) derived from Mouse a-Synuclein. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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anti-Synuclein (SYU) (N-Term), (pan) antibody
SYU 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synuclein (SYU) (AA 91-140), (pSer129) antibodySYU 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synuclein (SYU) (AA 15-64) antibodySYU 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "Expression and subcellular location of alpha-synuclein during mouse-embryonic development." in: Cellular and molecular neurobiology, Vol. 30, Issue 3, pp. 469-82, (2010) (PubMed).
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: "Expression and subcellular location of alpha-synuclein during mouse-embryonic development." in: Cellular and molecular neurobiology, Vol. 30, Issue 3, pp. 469-82, (2010) (PubMed).
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- Synuclein (SYU)
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别名
- Synuclein
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背景
- May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Takahashi T,
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分子量
- 18 kDa
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NCBI登录号
- NP_001035
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UniProt
- P37840
抗原
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