Merlin 抗体 (AA 516-520)
Quick Overview for Merlin 抗体 (AA 516-520) (ABIN362948)
抗原
See all Merlin (NF2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 516-520
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特异性
- The antibody detects endogenous level of total Merlin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Peptide sequence around AA 516-520 (R-L-S-M-E) derived from Human Merlin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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anti-Neurofibromin 2 (NF2) (AA 477-576) antibody
NF2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 230-414) antibodyNF2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 30-239) antibodyNF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 30-311) antibodyNF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (pSer518) antibodyNF2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (pSer518) antibodyNF2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 1-507) antibodyNF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (C-Term) antibodyNF2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 1-50), (pSer10) antibodyNF2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (C-Term) antibodyNF2 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Merlin (NF2) (Neurofibromin 2 (NF2))
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别名
- Merlin
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背景
- Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.
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分子量
- 69 kDa
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NCBI登录号
- NP_000259
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UniProt
- P35240
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途径
- Cell-Cell Junction Organization
抗原
-
