Synuclein 抗体 (AA 127-131)
-
- 抗原 See all Synuclein (SYU) products
- Synuclein (SYU)
-
抗原表位
- AA 127-131
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Synuclein antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous level of total Synuclein protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Peptide sequence around AA 127-131 (M-P-S-E-E) derived from Human a-Synuclein. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- 亚型
- IgG
-
anti-Synuclein (SYU) antibody
SYU 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein (SYU) (N-Term), (pan) antibodySYU 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synuclein (SYU) (AA 15-64) antibodySYU 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synuclein (SYU) (AA 91-140), (pSer129) antibodySYU 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Western blotting: 1:500-1:1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
- 抗原
- Synuclein (SYU)
- 别名
- Synuclein (SYU 产品)
- 背景
- SncA is a member of the synuclein family of structurally related proteins that are prominently expressed in the central nervous system, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and SncA and Snc-Beta inhibit phospholipase D2 selectively. SncA may serve to integrate presynaptic signaling and membrane trafficking. Aggregated SncA proteins form brain lesions that are hallmarks of neurodegenerative synucleinopathies. Defects in SncA play a role in the pathogenesis of Parkinson disease. SncA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer disease. SncA shares 95% sequence homology with rat SncA. Rat SncA is specifically expressed in brain and is associated with synaptosomal membranes in neurons
- 分子量
- 18 kDa
- NCBI登录号
- NP_000336
- UniProt
- P37840
-
