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HDAC4 抗体 (AA 630-634)

This anti-HDAC4 antibody is a 兔 多克隆 antibody detecting HDAC4 in WB 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN362744
发货至: 中国

Quick Overview for HDAC4 抗体 (AA 630-634) (ABIN362744)

抗原

See all HDAC4 抗体
HDAC4 (Histone Deacetylase 4 (HDAC4))

适用

  • 120
  • 49
  • 33
  • 6
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 109
  • 15
  • 1

克隆类型

  • 106
  • 19
多克隆

标记

  • 74
  • 8
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HDAC4 antibody is un-conjugated

应用范围

  • 86
  • 48
  • 29
  • 24
  • 20
  • 15
  • 14
  • 13
  • 11
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 630-634

    特异性

    The antibody detects endogenous level of total HDAC4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

    免疫原

    Peptide sequence around AA 630-634 (A-Q-S-S-P) derived from Human HDAC4. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunofluorescence: 1:100-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    HDAC4 (Histone Deacetylase 4 (HDAC4))

    别名

    HDAC4

    背景

    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

    分子量

    140 kDa

    NCBI登录号

    NP_006028

    UniProt

    P56524

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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