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Histone H3.1 抗体 (AA 8-12)

This anti-Histone H3.1 antibody is a 兔 多克隆 antibody detecting Histone H3.1 in WB 和 IF. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN362736
发货至: 中国

Quick Overview for Histone H3.1 抗体 (AA 8-12) (ABIN362736)

抗原

See all Histone H3.1 (HIST1H3B) 抗体
Histone H3.1 (HIST1H3B)

适用

  • 48
  • 16
  • 16
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 45
  • 3
  • 2

克隆类型

  • 45
  • 5
多克隆

标记

  • 38
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Histone H3.1 antibody is un-conjugated

应用范围

  • 37
  • 30
  • 26
  • 16
  • 15
  • 12
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 17
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-12

    特异性

    The antibody detects endogenous level of total Histone H3.1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

    免疫原

    Peptide sequence around AA 8-12 (R-K-S-T-G) derived from Human Histone H3.1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunofluorescence: 1:100-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Zhang, Zhou, Huang, Bi, Zhou: "Paeoniflorin reduced BLP-induced inflammatory response by inhibiting the NF-?B signal transduction in pathway THP-1 cells." in: Central-European journal of immunology / Polish Society for Immunology and eleven other Central-European immunological societies, Vol. 39, Issue 4, pp. 461-7, (2015) (PubMed).

    Zhang, Zhao, Li, Li, Cai, Shen, Shi, Li, Liu, Zhang, Ye: "The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 26, pp. 18961-74, (2013) (PubMed).

    Liao, Dong, Wu, Yang, Wang, Guo, Chen, Xu, Wen: "Resolvin D1 attenuates inflammation in lipopolysaccharide-induced acute lung injury through a process involving the PPAR?/NF-?B pathway." in: Respiratory research, Vol. 13, pp. 110, (2013) (PubMed).

    Chen, Evans, Evans: "FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short." in: PLoS ONE, Vol. 7, Issue 3, pp. e32971, (2012) (PubMed).

    Yu, Shan, Feng, Li, Zhu, Xie, Li, Li: "Triptolide ameliorates Crohn's colitis is associated with inhibition of TLRs/NF-?B signaling pathway." in: Fitoterapia, Vol. 82, Issue 4, pp. 709-15, (2011) (PubMed).

    Ma, Zhang, Zhong, Pan, Chen, Wang, Andrew, Ji, Han: "Decreased expression of profilin 2 in oral squamous cell carcinoma and its clinicopathological implications." in: Oncology reports, Vol. 26, Issue 4, pp. 813-23, (2011) (PubMed).

    Yao, Zhu, Zhao, Liu, Luo, Yin: "Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway." in: Journal of cellular biochemistry, Vol. 112, Issue 10, pp. 2837-49, (2011) (PubMed).

    Li, Zhang, Li, Wang, Wang, Han, Qian, Yang, Liu, Wei, Chen, Zhang, Zhang: "CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32660-8, (2008) (PubMed).

  • 抗原

    Histone H3.1 (HIST1H3B)

    别名

    Histone H3.1

    背景

    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    分子量

    17 kDa

    NCBI登录号

    NP_003521

    UniProt

    P68431
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