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Tumor Protein p73 抗体 (AA 97-101)

This anti-Tumor Protein p73 antibody is a 兔 多克隆 antibody detecting Tumor Protein p73 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN362626
发货至: 中国

Quick Overview for Tumor Protein p73 抗体 (AA 97-101) (ABIN362626)

抗原

See all Tumor Protein p73 (TP73) 抗体
Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

适用

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人, 小鼠, 大鼠

宿主

  • 115
  • 19

克隆类型

  • 106
  • 28
多克隆

标记

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This Tumor Protein p73 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    • 2
    • 1
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    • 1
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    • 1
    • 1
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    AA 97-101

    特异性

    The antibody detects endogenous level of total p73 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Peptide sequence around AA 97-101 (S-P-Y-A-Q) derived from Human P73. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

    别名

    p73

    背景

    This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters, alternate translation initiation sites, and multiple splice variations. Theoretically this can account for 29 different p73 isoforms, however, the biological validity and the full-length nature of most variants have not been determined.

    分子量

    80 kDa

    NCBI登录号

    NP_001119

    UniProt

    O15350

    途径

    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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