MEF2A 抗体 (AA 317-321)
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Quick Overview for MEF2A 抗体 (AA 317-321) (ABIN362560)
抗原
See all MEF2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 317-321
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特异性
- The antibody detects endogenous level of total MEF2A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Peptide sequence around AA 317-321 (V-T-T-P-S) derived from Human MEF2A. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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应用备注
- Immunohistochemistry: 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
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别名
- MEF2A
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背景
- The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain
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分子量
- 54 kDa
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NCBI登录号
- NP_001124
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UniProt
- Q02078
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
抗原
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