Cofilin1/2 (CFL1/2) (pTyr88) 抗体
Cited in 1 publication. This 兔 多克隆 anti-not_set antibody specifically detects not_set in IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
(1 reference)
产品编号 ABIN362442
发货至:
中国
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Quick Overview for Cofilin1/2 (CFL1/2) (pTyr88) 抗体 (ABIN362442)
抗原
See all Cofilin1/2 (CFL1/2) 抗体
Cofilin1/2 (CFL1/2)
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC)
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抗原表位
- pTyr88
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特异性
- The antibody detects endogenous level of cofilin1/cofilin2 only when phosphorylated at tyrosine 88.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- Peptide sequence around phosphorylation site of pTyr88 (A-T-Y (p) -E-T) derived from Human coflin1, cofilin2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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亚型
- IgG
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 1, pp. 70-9, (2009) (PubMed).
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: "DGCR6L, a novel PAK4 interaction protein, regulates PAK4-mediated migration of human gastric cancer cell via LIMK1." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 1, pp. 70-9, (2009) (PubMed).
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- Cofilin1/2 (CFL1/2)
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别名
- cofilin1/cofilin2
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背景
- Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
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分子量
- 19 kDa
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UniProt
- Q9Y281
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途径
- Tube Formation, CXCR4-mediated Signaling Events
抗原
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