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Cofilin 抗体 (pTyr139)

The 兔 多克隆 anti-Cofilin antibody (ABIN362440) specifically detects Cofilin in IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN362440
发货至: 中国
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Quick Overview for Cofilin 抗体 (pTyr139) (ABIN362440)

抗原

See all Cofilin (CFL1) 抗体
Cofilin (CFL1) (Cofilin 1 (CFL1))

适用

  • 161
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  • 7
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  • 1
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人, 小鼠, 大鼠

宿主

  • 158
  • 17
  • 2

克隆类型

  • 138
  • 38
多克隆

标记

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This Cofilin antibody is un-conjugated

应用范围

  • 100
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  • 13
  • 9
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Immunohistochemistry (IHC)
  • 抗原表位

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    • 1
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    • 1
    • 1
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    • 1
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    pTyr139

    特异性

    The antibody detects endogenous level of cofilin1 only when phosphorylated at tyrosine 139.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    Peptide sequence around phosphorylation site of pTyr139 (N-C-Y (p) -E-E) derived from Human cofilin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    Cofilin (CFL1) (Cofilin 1 (CFL1))

    别名

    cofilin1

    背景

    Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

    分子量

    19 kDa

    NCBI登录号

    NP_005498

    UniProt

    P23528

    途径

    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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