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GRIA2 抗体 (pSer880)

This anti-GRIA2 antibody is a 兔 多克隆 antibody detecting GRIA2 in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN362378
发货至: 中国

Quick Overview for GRIA2 抗体 (pSer880) (ABIN362378)

抗原

See all GRIA2 抗体
GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

适用

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人, 大鼠, 小鼠

宿主

  • 92
  • 26
  • 1

克隆类型

  • 80
  • 39
多克隆

标记

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This GRIA2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pSer880

    特异性

    The antibody detects endogenous level of Glutamate receptor 2 (Precursor) only when phosphorylated at serine 880.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    Peptide sequence around phosphorylation site of pSer880 (I-E-S (p) -V-K) derived from Human Glutamate receptor 2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

    别名

    Glutamate receptor 2 (Precursor)

    背景

    Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

    分子量

    100 kDa

    NCBI登录号

    NP_000817

    UniProt

    P42262

    途径

    PI3K-Akt Signaling
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