tau 抗体 (pSer422)
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北京 101111
Quick Overview for tau 抗体 (pSer422) (ABIN362343)
抗原
See all tau 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer422
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特异性
- The antibody detects endogenous level of Tau only when phosphorylated at serine 422.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- Peptide sequence around phosphorylation site of pSer422 (V-D-S (p) -P-Q) derived from Human Tau. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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亚型
- IgG
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anti-tau Protein (pSer396) antibody
适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (AA 677-707) antibody适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-tau Protein antibody适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 12F4 unconjugated
anti-tau Protein (AA 681-758) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tau Protein antibody (PerCP)适用: 人 WB, ELISA, IF, ICC, DB 宿主: 小鼠 Monoclonal 1D5 PerCP
anti-tau Protein antibody (PE)适用: 人 WB, ELISA, IF, ICC, DB 宿主: 小鼠 Monoclonal 1D5 PE
anti-tau Protein (pSer202), (pThr205) antibody (Atto 390)适用: 人 WB, ELISA, IHC, IF, ICC, DB 宿主: 兔 Monoclonal AH36 Atto 390
anti-tau Protein (pSer202), (pThr205) antibody (Atto 594)适用: 人 WB, ELISA, IHC, IF, ICC, DB 宿主: 兔 Monoclonal AH36 Atto 594
anti-tau Protein (pSer202), (pThr205) antibody (APC)适用: 人 WB, ELISA, IHC, IF, ICC, DB 宿主: 兔 Monoclonal AH36 APC
anti-tau Protein (pSer202), (pThr205) antibody (Biotin)适用: 人 WB, ELISA, IHC, IF, ICC, DB 宿主: 兔 Monoclonal AH36 Biotin
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应用备注
- Western blotting: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- tau (tau Protein)
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别名
- Tau
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背景
- Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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分子量
- 78 kDa
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UniProt
- P10636
抗原
-
