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BCR 抗体 (pTyr177)

This 兔 多克隆 anti-BCR antibody specifically detects BCR in WB 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN362226
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BCR 抗体 (pTyr177) (ABIN362226)

抗原

See all BCR 抗体
BCR (Breakpoint Cluster Region (BCR))

适用

  • 110
  • 55
  • 26
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 103
  • 5
  • 4

克隆类型

  • 96
  • 16
多克隆

标记

  • 63
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This BCR antibody is un-conjugated

应用范围

  • 80
  • 39
  • 35
  • 33
  • 26
  • 26
  • 19
  • 15
  • 12
  • 9
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 29
    • 16
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr177

    特异性

    The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 177.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    Peptide sequence around phosphorylation site of pTyr177 (P-F-Y (p) -V-N) derived from Human Bcr. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    BCR (Breakpoint Cluster Region (BCR))

    别名

    Bcr

    背景

    GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

    分子量

    210 kDa

    NCBI登录号

    NP_004318

    UniProt

    P11274

    途径

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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