-
- 抗原 See all Cofilin (CFL1) 抗体
- Cofilin (CFL1) (Cofilin 1 (CFL1))
-
抗原表位
- pSer3
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Cofilin antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 特异性
- The antibody detects endogenous level of cofilin only when phosphorylated at serine 3.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- 免疫原
- Peptide sequence around phosphorylation site of pSer3 (M-A-S (p) -G-V) derived from Human cofilin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product CFL1 Primary Antibody
-
-
- 应用备注
-
Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
Actin-regulated feedback loop based on Phactr4, PP1 and cofilin maintains the actin monomer pool." in: Journal of cell science, Vol. 126, Issue Pt 2, pp. 497-507, (2013) (PubMed).
: "Regulation of cofilin phosphorylation and asymmetry in collective cell migration during morphogenesis." in: Development (Cambridge, England), Vol. 138, Issue 3, pp. 455-64, (2011) (PubMed).
: "Downregulation of p57 accelerates the growth and invasion of hepatocellular carcinoma." in: Carcinogenesis, Vol. 32, Issue 12, pp. 1897-904, (2011) (PubMed).
: "H. R. Morgan, Astronomer." in: Science (New York, N.Y.), Vol. 126, Issue 3272, pp. 497, (2010) (PubMed).
: "
-
Actin-regulated feedback loop based on Phactr4, PP1 and cofilin maintains the actin monomer pool." in: Journal of cell science, Vol. 126, Issue Pt 2, pp. 497-507, (2013) (PubMed).
-
- 抗原
- Cofilin (CFL1) (Cofilin 1 (CFL1))
- 别名
- cofilin (CFL1 产品)
- 别名
- cfl1 antibody, xac1 antibody, xac2 antibody, cfl antibody, cb86 antibody, sb:cb86 antibody, zgc:56501 antibody, wu:fb18a04 antibody, wu:fk77b03 antibody, 12/8 antibody, ADF antibody, ADF/cofilin antibody, Adf antibody, CG4254 antibody, Cadf antibody, D-cof antibody, D61 antibody, Dmel\\CG4254 antibody, T8 antibody, Tsr antibody, cofilin antibody, cofilin/ADF antibody, cofilin/actin depolymerizing factor homolog antibody, l(2)03101 antibody, l(2)k03101 antibody, l(2)k05633 antibody, l(2)k13409 antibody, ntf antibody, CFL antibody, AA959946 antibody, Cof antibody, CFL1 antibody, cofilin 1 (non-muscle) L homeolog antibody, cofilin 1 (non-muscle) antibody, cofilin 1 (non-muscle), like antibody, cofilin 1 antibody, twinstar antibody, cofilin antibody, cofilin 1, non-muscle antibody, Contrafreeloading antibody, cfl1.L antibody, cfl1 antibody, cfl1l antibody, CFL1 antibody, tsr antibody, COF1 antibody, TSTA_042790 antibody, Cfl1 antibody, CFL antibody
- 背景
- Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
- 分子量
- 19 kDa
- NCBI登录号
- NP_005498
- UniProt
- P23528
- 途径
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
-