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SYT1 抗体 (pSer309)

This anti-SYT1 antibody is a 兔 多克隆 antibody detecting SYT1 in WB 和 IHC. Suitable for 大鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN361497
发货至: 中国

Quick Overview for SYT1 抗体 (pSer309) (ABIN361497)

抗原

See all SYT1 抗体
SYT1 (Synaptotagmin I (SYT1))

适用

  • 80
  • 69
  • 47
  • 11
  • 7
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
大鼠

宿主

  • 92
  • 12
  • 6
  • 2
  • 1
  • 1

克隆类型

  • 102
  • 12
多克隆

标记

  • 68
  • 8
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SYT1 antibody is un-conjugated

应用范围

  • 70
  • 43
  • 36
  • 16
  • 14
  • 13
  • 13
  • 10
  • 9
  • 5
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 13
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer309

    特异性

    Specific for the ~60k-62k synaptotagmin protein phosphorylated at Ser309.

    交叉反应

    大鼠

    预测反应

    bovine, canine, chicken, human, mouse, non-human primate, zebra fish

    纯化方法

    Antigen Affinity Purified from Pooled Serum

    免疫原

    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser309 conjugated to KLH
  • 应用备注

    Recommended Dilution: WB: 1:1000 IHC: 1:400 Quality Control: Western blots performed on each lot.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    储存条件

    -20 °C
  • Leal-Ortiz, Waites, Terry-Lorenzo, Zamorano, Gundelfinger, Garner: "Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis." in: The Journal of cell biology, Vol. 181, Issue 5, pp. 831-46, (2008) (PubMed).

    Poskanzer, Marek, Sweeney, Davis: "Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo." in: Nature, Vol. 426, Issue 6966, pp. 559-63, (2003) (PubMed).

    Wang, Lu, Bai, Chang, Martin, Chapman, Jackson: "Different domains of synaptotagmin control the choice between kiss-and-run and full fusion." in: Nature, Vol. 424, Issue 6951, pp. 943-7, (2003) (PubMed).

    Fernández-Chacón, Königstorfer, Gerber, García, Matos, Stevens, Brose, Rizo, Rosenmund, Südhof: "Synaptotagmin I functions as a calcium regulator of release probability." in: Nature, Vol. 410, Issue 6824, pp. 41-9, (2001) (PubMed).

    Hilfiker, Pieribone, Nordstedt, Greengard, Czernik: "Regulation of synaptotagmin I phosphorylation by multiple protein kinases." in: Journal of neurochemistry, Vol. 73, Issue 3, pp. 921-32, (1999) (PubMed).

  • 抗原

    SYT1 (Synaptotagmin I (SYT1))

    别名

    SYT1

    分子量

    60/62 kDa

    基因ID

    25716

    UniProt

    P21707

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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