我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

GRIN2B 抗体 (pTyr1472)

Name: GRIN2B 抗体 (pTyr1472)
Brand: antibodies-online
SKU: ABIN361485
Availability: OutOfStock

Cited in 6+ publications. This anti-GRIN2B antibody is a 兔多克隆 antibody detecting GRIN2B in WB 和 ELISA. Suitable for 大鼠.

Western blots of rat hippocampal lysate showing specific immunolabeling of the ~180k NR2B subunit of the NMDAR phosphorylated at Tyr1472 (Control). (GRIN2B 抗体 (pTyr1472))

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180 kDa NR2B subunit of the NMDAR phosphorylated at Tyr1472 in the first lane (-). (GRIN2B 抗体 (pTyr1472))

2 images

(6 references)

产品编号 ABIN361485

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GRIN2B 抗体 (pTyr1472) (ABIN361485)

抗原

See all GRIN2B 抗体

GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This GRIN2B antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

Discover our top product GRIN2B Primary Antibody

抗原表位
34

33

22

22

21

19

16

12

10

5

4

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr1472

特异性

Specific for endogenous levels of the ~180 kDa NMDAR NR2B-subunit protein phosphorylated at Tyr1472. Immunolabeling is completely eliminated by treatment with λ-phosphatase.

交叉反应

小鼠, 大鼠

预测反应

bovine, canine, chicken, human, non-human primate, zebra fish

产品特性

Our NMDA NR2B Subunit (Tyr1472) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects NMDA NR2B Subunit (Tyr1472) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

纯化方法

Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

免疫原

Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1472 of the NR2B subunit of the rat NMDA receptor, conjugated to keyhole limpet hemocyanin (KLH).

亚型

IgG
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 27-163) antibody
GRIN2B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E9A8 unconjugated

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (HRP)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 HRP

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (FITC)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 FITC

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Biotin)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Biotin

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PE)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 PE

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (APC)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 APC

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (PerCP)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 PerCP

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 488)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 488

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 594)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 594

anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) (AA 20-271) antibody (Atto 390)
GRIN2B 适用: 大鼠 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S59 Atto 390

应用备注

Dilution Range: ICC: 1:100
Dilution Range: WB Brain: 1:1000
Dilution Range: WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

储存条件

-20 °C

储存方法

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

有效期

12 months
Knox, Brennan-Minnella, Lu, Yang, Nakazawa, Yamamoto, Swanson, Ferriero, Jiang: "NR2B phosphorylation at tyrosine 1472 contributes to brain injury in a rodent model of neonatal hypoxia-ischemia." in: Stroke; a journal of cerebral circulation, Vol. 45, Issue 10, pp. 3040-7, (2014) (PubMed).

Gladding, Sepers, Xu, Zhang, Milnerwood, Lombroso, Raymond: "Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model." in: Human molecular genetics, Vol. 21, Issue 17, pp. 3739-52, (2012) (PubMed).

Castillo, Norcini, Baquero-Buitrago, Levacic, Medina, Montoya-Gacharna, Blanck, Dubois, Recio-Pinto: "The NMDA-evoked cytoplasmic calcium increase in adult rat DRG neuronal somata was potentiated by SP pretreatment in a PKC-dependent manner." in: Neuroscience, (2011) (PubMed).

Carreño, Walch, Dutta, Nedungadi, Cunningham: "Brain-Derived Neurotrophic Factor-Tyrosine Kinase B Pathway Mediates NMDA Receptor NR2B Subunit Phosphorylation in the Supraoptic Nuclei Following Progressive Dehydration." in: Journal of neuroendocrinology, Vol. 23, Issue 10, pp. 894-905, (2011) (PubMed).

Venkitaramani, Moura, Picciotto, Lombroso: "Striatal-enriched protein tyrosine phosphatase (STEP) knockout mice have enhanced hippocampal memory." in: The European journal of neuroscience, Vol. 33, Issue 12, pp. 2288-98, (2011) (PubMed).

Hicklin, Wu, Radcliffe, Freund, Goebel-Goody, Correa, Proctor, Lombroso, Browning: "Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 16, pp. 6650-5, (2011) (PubMed).
抗原

GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

别名

GRIN2B

背景

Synonyms: EPND antibody, FESD antibody, GluN2A antibody, Glutamate [NMDA] receptor subunit epsilon-1 antibody, Glutamate receptor antibody, Glutamate receptor ionotropic N methyl D aspartate 2A antibody, GRIN 2A antibody, GRIN2A antibody, hNR2A antibody, LKS antibody, N methyl D aspartate receptor channel subunit epsilon 1 antibody, N Methyl D Aspartate Receptor Subtype 2A antibody, N methyl D aspartate receptor subunit 2A antibody, N-methyl D-aspartate receptor subtype 2A antibody, NMDA receptor subtype 2A antibody, NMDAR 2A antibody, NMDAR2A antibody, NMDE1_HUMAN antibody, NR2A antibody, OTTHUMP00000160135 antibody, OTTHUMP00000174531 antibody
Description Logic: Our NMDA NR2B Subunit (Tyr1472) rabbit polyclonal phosphospecific primary antibody is produced . It detects NMDA NR2B Subunit (Tyr1472) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
Gene Name Alternatives: GRIN2B

分子量

180 kDa

基因ID

24410

UniProt

Q00960

途径

Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity