(1 reference)-
- 抗原 See all GRIA2 抗体
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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抗原表位
- pSer880
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRIA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody has been directly tested for reactivity in Western blots in rat tissues. It is anticipated that the antibody will react with chicken, human, mouse, non-human primate and Zebrafish tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen. Specific for ~100k phosphorylated at Ser880.
- 交叉反应
- 大鼠
- 预测反应
- human, mouse, non-human primate, Zebrafish
- 纯化方法
- Antigen Affinity Purified from Pooled Serum
- 免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser880 conjugated to KLH
- Top Product
- Discover our top product GRIA2 Primary Antibody
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anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) antibody
GRIA2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibodyGRIA2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7G6 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 35-175) antibodyGRIA2 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 7A7A3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 413-527) antibodyGRIA2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 175-430) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibodyGRIA2 适用: 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) antibodyGRIA2 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) antibodyGRIA2 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
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: "Cortical development of AMPA receptor trafficking proteins." in: Frontiers in molecular neuroscience, Vol. 5, pp. 65, (2012) (PubMed).
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: "Cortical development of AMPA receptor trafficking proteins." in: Frontiers in molecular neuroscience, Vol. 5, pp. 65, (2012) (PubMed).
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- 抗原
- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
- 别名
- GRIA2 (GRIA2 产品)
- 别名
- GLUR2 antibody, GLURB antibody, GluA2 antibody, GluR-K2 antibody, HBGR2 antibody, GluR-2 antibody, GluR-B antibody, Glur-2 antibody, Glur2 antibody, GluR2 antibody, gluR-B antibody, glur2a antibody, gria2.1 antibody, zfGRIA2[a] antibody, glur2 antibody, glutamate ionotropic receptor AMPA type subunit 2 antibody, glutamate receptor, ionotropic, AMPA 2 antibody, glutamate receptor, ionotropic, AMPA2 (alpha 2) antibody, glutamate receptor, ionotropic, AMPA 2a antibody, glutamate receptor, ionotropic, AMPA 2 S homeolog antibody, GRIA2 antibody, Gria2 antibody, gria2a antibody, gria2.S antibody
- 背景
- Affinity purified rabbit polyclonal antibody. Biological Significance: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Kein nen et al., 1990, Hollmann and Heinemann, 1994). The number of GluR2 subunits in the AMPA receptor complex affects the Ca2+ permeability, rectification and single-channel conductance of AMPA receptors. Ser880 has been identified as the PKC phosphorylation site within the C-terminal region of GluR2 and has been shown to differentially regulate the interaction of the PDZ domain-containing proteins GRIP1 and PICK 1 (Matsuda et al., 1999) Anti-Phospho-Ser880 GluR2 Western blot of rat brain homogenate showing specific immunolabeling of the ~100k GluR2 protein phosphorylated at Ser880 (control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown).
- 分子量
- '100 kDa
- 基因ID
- 29627
- UniProt
- P19491
- 途径
- PI3K-Akt Signaling
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