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GRIA2 抗体

This anti-GRIA2 antibody is a 兔 多克隆 antibody detecting GRIA2 in WB. Suitable for 大鼠.
产品编号 ABIN361453
发货至: 中国

Quick Overview for GRIA2 抗体 (ABIN361453)

抗原

See all GRIA2 抗体
GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

适用

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大鼠

宿主

  • 88
  • 18
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克隆类型

  • 77
  • 30
多克隆

标记

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This GRIA2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    Specific for the ~100k GluR2 protein.

    交叉反应

    大鼠

    预测反应

    chicken, human, mouse, non-human primate, Zebrafish

    纯化方法

    Antigen Affinity Purified from Pooled Serum

    免疫原

    Synthetic peptide corresponding to amino acid residues specific to GluR2 conjugated to KLH
  • 应用备注

    Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    储存条件

    -20 °C
  • 抗原

    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

    别名

    GRIA2

    背景

    The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003) Anti-GluR2 Western blot of a rat hippocampal (Hipp) lysate showing the specific immunolabeling of the ~100k GluR2 protein.

    分子量

    '100 kDa

    基因ID

    29627

    UniProt

    P19491

    途径

    PI3K-Akt Signaling
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