Choline Acetyltransferase 抗体
Quick Overview for Choline Acetyltransferase 抗体 (ABIN361419)
抗原
See all Choline Acetyltransferase (CHAT) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the ~ 70k choline acetyltransferase protein
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交叉反应
- Bird (Avian), 小鸡, 豚鼠, 人, 小鼠, Non-Human Primate
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纯化方法
- Affinity Purified
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免疫原
- Native choline acetyltransferase purifed from human placenta
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anti-Choline O-Acetyltransferase (CHAT) (AA 517-732) antibody
CHAT 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 331-630) antibodyCHAT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 98-128) antibodyCHAT 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 101-200) antibodyCHAT 适用: 人, 小鼠, 大鼠, 犬 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 354-592) antibodyCHAT 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (C-Term) antibodyVerified CHAT 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 446-652) antibodyCHAT 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) antibodyMicroarray verified CHAT 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB872084 unconjugated
anti-Choline O-Acetyltransferase (CHAT) (N-Term) antibody (HRP)CHAT 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Choline O-Acetyltransferase (CHAT) (N-Term) antibody (FITC)CHAT 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
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应用备注
- Recommended Dilution: WB: 1:100 IHC: 1:100 Quality Control: Western blots performed on each lot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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别名
- CHAT
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背景
- Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999). Anti-Choline Acetyltransferase Western blot of rat brain lysate showing specific immunolabeling of the ~70k ChAT
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分子量
- '70 kDa
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基因ID
- 1103
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途径
- Skeletal Muscle Fiber Development
抗原
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