Tryptophan Hydroxylase 1 抗体
Quick Overview for Tryptophan Hydroxylase 1 抗体 (ABIN361412)
抗原
See all Tryptophan Hydroxylase 1 (TPH1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the ~55k tryptophan hydroxylase protein.
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交叉反应
- 人, 大鼠
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预测反应
- wide variety mammalian
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纯化方法
- Antigen Affinity Purified from Pooled Serum
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免疫原
- Recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE
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anti-Tryptophan Hydroxylase 1 (TPH1) (Internal Region) antibody
TPH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 35-62), (N-Term) antibodyTPH1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21510 unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 257-405) antibodyTPH1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (pSer58) antibodyTPH1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 345-444) antibodyTPH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (N-Term) antibodyTPH1 适用: 人, 小鼠, 大鼠, 兔, 小鸡 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 26-75) antibodyTPH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (AA 231-280) antibodyTPH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) antibodyTPH1 适用: 人 WB, IHC, IF/ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tryptophan Hydroxylase 1 (TPH1) (pSer260) antibodyTPH1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended Dilution: WB: 1:1000 IHC (frozen sections, Haycock et al., 2002): 1:1000 Quality Control: Western blots performed on each lot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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- Tryptophan Hydroxylase 1 (TPH1)
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别名
- TPH1
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背景
- Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin (Martinez et al., 2001). Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland (Haycock et al., 2002) . Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis (Martinez et al., 2001). Anti-Tryptophan Hydroxylase Western blot of human dorsal Raphe nucleus showing specifc immunolabeling of the ~55k tryptophan hydroxylase protein.
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分子量
- '55 kDa
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基因ID
- 100101558
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UniProt
- P17290
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途径
- Feeding Behaviour
抗原
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